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John Q. Zhang, Ph.D. Staff Research Associate UC Davis Genome Center email:qjzhang phone:(530)752-2237 |
Research Interest
Molecular and Cellular Biology
Next Generation DNA Sequencing
Metagenomics
Education
Ph.D., (Cell Biology), Peking Union Medical College, Beijing, China, 1988
Bachelor, Shangdong University, Jinan, China, 1979 - 1983
Accomplishments
Outstanding record in genomic DNA library construction for next generation
DNA sequencing (Illuminar, Roche 454)
Outstanding record in in situ hybridization for SIV gene expression analyses
Provide support in molecular biological technical area
Completed the physical map of chicken fast myosin heavy chain gene cluster.
Submission to Genbank of 4 full length (~6kb each) chicken fast myosin heavy chain
gene cDNA sequences (Original work). Genbank Accession: Cemb2 cDNA: AF272033, Cemb3 cDNA: AF272034, CN101 cDNA: AY116217, CN127 cDNA: AY116218
Experience
Staff Research Associate, Genome Center, UC Davis, July 2011- Present
Staff Research Associate, Center for Comparative Medicine, UC Davis, 2004 – June 2011
Staff Research Associate, laboratory Manger/Supervisor, Food Science & Technology,
UC Davis, 1994 – 2004
Staff Research Associate, Section of Molecular & Cellular Biology, Division of
Biological Sciences, UC Davis, 1992 – 1993
Post Doctoral Training, Department of Genetics, University of California at Davis,
1989-1991
Special Skills
Well versed in Cell Biology and Molecular Biology
Expertise in PCR, DNA cloning, library construction, cell culture
Many years of experience in lab management and supervision
Skilled in experimental design and troubleshooting
Publications
Zhang Q; Reddy PM; Yu CY; Bastiani C; Higgs D; Stamatoyannopoulos G; Papayannopoulou T; Shen CK. Transcriptional activation of human z2 globin
promoter by the a globin regulatory element (HS-40): functional role
of specific nuclear factor-DNA complexes. Mol. Cell. Biol., 1993, 13(4):2298-308
Zhang Q; Rombel I; Reddy GN; Gang JB; Shen CK. Functional roles of in vivo footprinted DNA motifs within an alpha-globin enhancer. Erythroid lineage and developmental stage specificities. J. Biol. Chem., 1995, 270(15):8501-5
Zhang, Q; Reddy, S; Shen, C K J. Enhancer-Promoter Interaction and Transcriptional Activation of z Globin Gene in Embryonic Erythroid Cells. FASEB Journal, v.7, n.7, 1993: A1218
Zhang, Q; Xue, S-F. Studies on the cell phenotype characteristics of hybrid cells crossed between rat nucleated erythroblasts and mouse plasmacytoma (SP2/O) cell line. Science in China, Series B Chemistry Life Sciences & Earth Sciences, v.33, n.5, (1990): 572-583.
Bandman E, Arrizubieta MJ, Wick M, Hattori A, Tablin F, Zhang S, Zhang Q. Functional analysis of the chicken sarcomeric myosin rod: regulation of dimerization, solubility, and fibrillogenesis. Cell Struct Funct. 1997 Feb;22(1):131-7. Review
Zhang, Q; Rombel I; Reddy G. N; and Shen CK. Transcriptional Regulation of Human z2 and a Globin Promoters by Multiple Nuclear Factor-DNA Complexes: the Final Act. In Stamatoyannopoulos G (ed): Hemoglobin Switching. 1995. Chapter 16, p. 193-202
